The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 12, 2006

Filed:

Apr. 14, 2005
Applicants:

Takashi Hayama, Ibaraki, JP;

Nobuhiko Kawanishi, Ibaraki, JP;

Tooru Takaki, Ibaraki, JP;

Inventors:

Takashi Hayama, Ibaraki, JP;

Nobuhiko Kawanishi, Ibaraki, JP;

Tooru Takaki, Ibaraki, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/58 (2006.01); A01N 43/60 (2006.01); A61K 31/50 (2006.01); A61K 31/495 (2006.01); C07D 471/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to a compound of the general formula (I): [Aris aryl fused to the adjacent pyrazinone ring at the 5th and 6th positions, etc., X is CO, etc., Y is CH, etc., Z is CH, etc., V is CH, etc., Wis —(CH)— (n is zero to four), R, is H or optionally substituted lower alkyl, etc., Ris H, etc., Rand Rare the same or different and are each H, etc., Rand Rare the same or different and are each H, hydroxy, etc.] or a pharmaceutically acceptable salt or ester thereof; a pharmaceutical composition, an inhibitor of Cdk4 and/or Cdk6 or an anti-cancer agent, containing the same as an active ingredient; and a process for preparing them.


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