The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 12, 2006
Filed:
Jun. 20, 2003
Sean D. Monahan, Madison, WI (US);
Jon A. Wolff, Madison, WI (US);
Paul M. Slattum, Madison, WI (US);
James E. Hagstrom, Middleton, WI (US);
Vladimir G. Budker, Middleton, WI (US);
David B. Rozema, Madison, WI (US);
Sean D. Monahan, Madison, WI (US);
Jon A. Wolff, Madison, WI (US);
Paul M. Slattum, Madison, WI (US);
James E. Hagstrom, Middleton, WI (US);
Vladimir G. Budker, Middleton, WI (US);
David B. Rozema, Madison, WI (US);
Mirus Bio Corporation, Madison, WI (US);
Abstract
Disclosed is a process for transfecting genetic material into a mammalian cell to alter endogenous properties of the cell. The process comprises designing a polynucleotide for transfection. Then the polynucleotide is inserted into a mammalian vessel such as a tail vein or artery. Prior to insertion, subsequent to insertion, or concurrent with insertion the permeability of the vessel is increased thereby the genetic material is delivered to the parenchymal cell altering endogenous properties of the cell.