The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 12, 2006
Filed:
Jan. 16, 2004
Randall B. Lauffer, Brookline, MA (US);
Thomas J. Mcmurry, Winchester, MA (US);
Stephen O. Dunham, Madison, NJ (US);
Daniel M. Scott, Acton, MA (US);
David J. Parmelee, Belmont, MA (US);
Stéphane Dumas, Cambridge, MA (US);
Randall B. Lauffer, Brookline, MA (US);
Thomas J. McMurry, Winchester, MA (US);
Stephen O. Dunham, Madison, NJ (US);
Daniel M. Scott, Acton, MA (US);
David J. Parmelee, Belmont, MA (US);
Stéphane Dumas, Cambridge, MA (US);
Epix Pharmaceuticals, Inc., Cambridge, MA (US);
Abstract
The present invention relates to improved diagnostic agents for Magnetic Resonance Imaging and optical imaging. In particular, this invention relates to MRI and optical imaging agents that allow for the sensitive detection of a specific bioactivity within a tissue. These agents are prodrug contrast agents which are bioactivated in vivo in the presence of the specific bioactivity. This invention also relates to pharmaceutical compositions comprising these agents and to methods of using the agents and compositions comprising the agents.