The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 05, 2006
Filed:
Mar. 28, 2003
Kristian Stromgaard, New York, NY (US);
Makiko Suehiro, White Plains, NY (US);
Koji Nakanishi, New York, NY (US);
Stine B. Vogensen, Copenhagen, DK;
Kristian Stromgaard, New York, NY (US);
Makiko Suehiro, White Plains, NY (US);
Koji Nakanishi, New York, NY (US);
Stine B. Vogensen, Copenhagen, DK;
The Trustees of Columbia University in the City of New York, New York, NY (US);
Abstract
The subject invention provides compounds having the structure: wherein Ris H, OH, a photoactivatable moiety, a fluorescent moiety, or a radioactive moiety; Ris H, OH, a photoactivatable moiety, a fluorescent-moiety, or a radioactive moiety; Ris H or OH; Ris H, OH, a photoactivatable moiety, a fluorescent moiety, or a radioactive moiety; and wherein at least one of R, R, R, or Ris a photoactivatable moiety, a fluorescent moiety, or a radioactive moiety, or an optically pure enantiomer of the compound or wherein R1 is H or OH; R2 is H, OH, halogen, unsubstituted or substituted, straight or branched (C–C) alkyl group, (C–C) alkenyl, or a (C–C) alkynyl, (C–C) alkoxy, (C–C) alkenyloxy, or (C–C) alkynyloxy, —N3, —COR5, —CONR5R6, —CO2R5, —OCOR5, —NH(OH), —NR5R6, —NHCOR5, —N(OH)COR5, —CH2OR5, —OCH2CO2R5, —CH2SR5, —CH2NR5R6, —SR5, —OSR5, or —NR5SO2R6, where R5 and R6 are each independently hydrogen, substituted or unsubstituted (C–C) alkyl, (C–C) alkenyl, or (C–C) alkynyl, or a cycloalkyl or aryl group having 3 to 10 carbon atoms; R3 is H or OH; R4 is H, (C1–C10) alkyl, (C1–C10) alkenyl, (C1–C10) alkynyl, -A-Ar, -A-Z-Ar, —SO—Ar, or -A-NR, or —R, where A, Z and Ar are as defined herein, and the use of the compounds for detecting or identifying a receptor which binds the compounds of the invention or for treating a PAF associated condition in a subject.