The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 05, 2006

Filed:

Mar. 29, 2004
Applicants:

Mark R. Burns, Shoreline, WA (US);

Gerard F. Graminski, Shoreline, WA (US);

Inventors:

Mark R. Burns, Shoreline, WA (US);

Gerard F. Graminski, Shoreline, WA (US);

Assignee:

MediQuest Therapeutics, Inc., Bothell, WA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/135 (2006.01); C07D 211/18 (2006.01);
U.S. Cl.
CPC ...
Abstract

Novel polyamines, their synthesis and use in pharmacological, cosmetic or agricultural applications are provided. The polyamines induce antizyme production which in turn down regulates both the production of polyamines by omithine decarboxylase (ODC) and the transport of polyamines by its corresponding polyamine transporter. These compounds will preferably enter the cell independent of the polyamine transporter. As drugs, these compounds are used to treat any disease associated with cellular proliferation including but not limited to cancer.


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