The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 05, 2006
Filed:
Apr. 05, 2000
Dorit Baucke, Mannheim, DE;
Helmut Mack, Ludwigshafen, DE;
Werner Seitz, Plankstadt, DE;
Wilfried Hornberger, Neustadt, DE;
Gisela Backfisch, Dossenheim, DE;
Juergen Delzer, Speyer, DE;
Dorit Baucke, Mannheim, DE;
Helmut Mack, Ludwigshafen, DE;
Werner Seitz, Plankstadt, DE;
Wilfried Hornberger, Neustadt, DE;
Gisela Backfisch, Dossenheim, DE;
Juergen Delzer, Speyer, DE;
Abbott GmbH & Co. KG, Wiesbaden, DE;
Abstract
The present invention relates to prodrugs of pharmacologically active five-membered heterocyclic amidines from which are produced in vivo compounds which are competitive inhibitors of trypsin-like serine proteases, in particular thrombin and kininogenases such as kallikrein, to the preparation thereof and to the use thereof as medicines. The invention also relates to pharmaceutical compositions which comprise the prodrugs of the active compounds as ingredients, and to the use of the compounds as thrombin inhibitors, anticoagulants and as antiinflammatory agents.