The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 05, 2006
Filed:
Dec. 11, 2000
Helen Jane Bryant, Roydon, GB;
Mark Stuart Chambers, Puckeridge, GB;
Philip Jones, Bishop Stortford, GB;
Angus Murray Macleod, Bishop Stortford, GB;
Robert James Maxey, Amersham, GB;
Helen Jane Bryant, Roydon, GB;
Mark Stuart Chambers, Puckeridge, GB;
Philip Jones, Bishop Stortford, GB;
Angus Murray MacLeod, Bishop Stortford, GB;
Robert James Maxey, Amersham, GB;
Merck Sharp & Dohme Ltd., Hoddesdon, GB;
Abstract
The present invention provides a compound of formula (I) in which Ris generally hydrogen or CF, Ris generally hydrogen, W is a cyclic amine, a heterocycle or a group L-Y—X where L-Y is a linking portion and X is generally an aromatic or non-aromatic heterocycle, alkyl or alkylcarbonyl and Z is generally a heterocycle such as 5-methylisoxazol-3-yl, and pharmaceutically acceptable salts thereof for enhancing cognition in conditions such as Alzheimer's Disease, pharmaceutical compositions comprising them, their use for manufacturing medicaments and methods of treatment using them