The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 05, 2006
Filed:
Nov. 21, 2003
Yong-jin Wu, Madison, CT (US);
Alexandre L'heureux, Longueuil, CA;
Li-qiang Sun, Glastonbury, CT (US);
Yong-Jin Wu, Madison, CT (US);
Alexandre L'Heureux, Longueuil, CA;
Li-Qiang Sun, Glastonbury, CT (US);
Bristol-Myers Squibb Company, Princeton, NJ (US);
Abstract
The present invention provides novel arylcyclopropylcarboxylic amides and related derivatives having the general Formula I wherein R, R, R, R, R, R, Rand Rare as defined in the specification, or a nontoxic pharmaceutically acceptable salt, solvate or hydrate thereof which are openers or activators of KCNQ potassium channels. The present invention also provides pharmaceutical compositions comprising said arylcyclopropylcarboxylic amides and to the method of treatment of disorders sensitive to KCNQ potassium channel opening activity such as migraine or a migraine attack, bipolar disorders, epilepsy, acute and chronic pain and anxiety.