The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 28, 2006

Filed:

Jul. 18, 2003
Applicants:

William R. Gamble, Longmont, CO (US);

Zhengjie Liu, Superior, CO (US);

David T. Bailey, Boulder, CO (US);

Pedro P. Perez, Hialeah, FL (US);

Dean P. Stull, Longmont, CO (US);

Steven L. Richheimer, Westminster, CO (US);

Rebecca L. Nichols, Broomfield, CO (US);

Rod Lenoble, Westminster, CO (US);

Inventors:

William R. Gamble, Longmont, CO (US);

Zhengjie Liu, Superior, CO (US);

David T. Bailey, Boulder, CO (US);

Pedro P. Perez, Hialeah, FL (US);

Dean P. Stull, Longmont, CO (US);

Steven L. Richheimer, Westminster, CO (US);

Rebecca L. Nichols, Broomfield, CO (US);

Rod Lenoble, Westminster, CO (US);

Assignee:

Wyeth, Madison, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/045 (2006.01); C07C 29/76 (2006.01); C07C 29/28 (2006.01); C07C 29/86 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention provides an isolated mixture of higher molecular weight primary aliphatic alcohols having 20, 22, 24, 26, 27, 28, 30, 32 and 34 carbon atoms and having enhanced purity. This invention also provides a process for obtaining the alcohol mixture by extracting a natural product with organic solvents with or without saponification of the natural product. The alcohol mixture is useful in pharmaceutical compositions, foodstuffs and dietary supplements and is effective for lowering total cholesterol and LDL-cholesterol and increasing HDL-cholesterol levels and therefore is effective in treating hypercholesterolemia. The composition may be used to reduce the risk of coronary heart disease, to inhibit the atherosclerotic process (platelet hyperaggregability, ischemia and thrombosis), and can be used as an anti-inflammatory and anti-thrombotic agent. The composition also possesses neurotrophic properties and is useful for improving male sexual activity.


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