The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 28, 2006
Filed:
Apr. 26, 2001
Michael Volker, D-50678 Köln, DE;
Michael Becka, D-59469 Ense, DE;
Werner Kroll, D-42659 Solingen, DE;
Andreas Knorr, D-40699 Erkrath, DE;
Mathias Gehrmann, D-51373 Leverkusen, DE;
Guido Hennig, 50859 Köln, DE;
Sylvia Unger, D-69420 Heidelberg, DE;
Elmar-reinhold Burchardt, D-58239 Schwerte, DE;
Michael J. Arthur, West Wellow Hampshire S051 6BY, GB;
Alastair D. Burt, Fairmoor Morphet Northumberland NE 613 JL, GB;
Massimo Pinzani, I-50018 Scandicci, IT;
Detlef Schuppan, D-91088 Bubenreuth, DE;
Michael Volker, D-50678 Köln, DE;
Michael Becka, D-59469 Ense, DE;
Werner Kroll, D-42659 Solingen, DE;
Andreas Knorr, D-40699 Erkrath, DE;
Mathias Gehrmann, D-51373 Leverkusen, DE;
Guido Hennig, 50859 Köln, DE;
Sylvia Unger, D-69420 Heidelberg, DE;
Elmar-Reinhold Burchardt, D-58239 Schwerte, DE;
Michael J. Arthur, West Wellow Hampshire S051 6BY, GB;
Alastair D. Burt, Fairmoor Morphet Northumberland NE 613 JL, GB;
Massimo Pinzani, I-50018 Scandicci, IT;
Detlef Schuppan, D-91088 Bubenreuth, DE;
Other;
Abstract
The present invention concerns a method for diagnosing liver fibrosis wherein two or more diagnostic markers are measured and the measurements are correlated by a mathematic algorithm characterized in that the diagnostic markers are selected from the group N-terminal procollagen III propeptide (PIIINP), Collagen IV, Collagen VI, Tenascin, Laminin, Hyaluronan, MMP-2, TIMP-1 and MMP-9/TIMP-1 complex. The algorithm can be used to predict the histological score of a liver biopsy.