The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 21, 2006
Filed:
Jan. 22, 2004
Robert E. Lewis, Milford, NH (US);
Fu-min Su, Seattle, WA (US);
Timothy A. Lane, Salem, NH (US);
Keith R. Olewine, Merrimack, NH (US);
Peter S. Holton, Lexington, MA (US);
Robert E. Lewis, Milford, NH (US);
Fu-Min Su, Seattle, WA (US);
Timothy A. Lane, Salem, NH (US);
Keith R. Olewine, Merrimack, NH (US);
Peter S. Holton, Lexington, MA (US);
Bristol-Myers Squibb Pharma Company, Princeton, NJ (US);
Abstract
Methods and apparatus for separating ions of metallic elements are provided. Preferred methods utilize a hydrophobic chelating extractant, such as an organophosphorus compound, adsorbed onto carbon or graphite fibers in the form of felt. Also described is a new thallium-201 generator that comprises a column containing an acidic organophosphorus extractant adsorbed on carbon or graphite fibers, and a yttrium-90 generator system comprised of two extraction columns designed to selectively absorb yttrium-90 at different pH, to enable the separation of yttrium-90 from strontium-90. The two columns are connected in series for stepwise separation. The yttrium-90 product is freed from residual strontium-90 and metal contaminants and can be eluted from the second column with dilute acid, acetate buffer, water or saline for labeling biological targeted molecules. The new generator system provides rapid and efficient separation of yttrium-90 and is amenable to both scale-up and automation. Also described is a newTc generator that comprises a column containing an acidic organophosphorus extractant adsorbed on carbon or graphite fibers designed to selectively absorbMo at a selected pH, to enable the separation ofTc fromMo.