The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 21, 2006
Filed:
Aug. 26, 2004
Yong-soo Bae, Suwon, KR;
Sang-gu Lee, Daejeon Metropolitan, KR;
Hye-rhan Jeong, Daejeon Metropolitan, KR;
Dong-sung Lee, Daejeon Metropolitan, KR;
Ki-tae Kim, Daejeon Metropolitan, KR;
Dae-you Kim, Daejeon Metropolitan, KR;
Yong-Soo Bae, Suwon, KR;
Sang-Gu Lee, Daejeon Metropolitan, KR;
Hye-Rhan Jeong, Daejeon Metropolitan, KR;
Dong-Sung Lee, Daejeon Metropolitan, KR;
Ki-Tae Kim, Daejeon Metropolitan, KR;
Dae-You Kim, Daejeon Metropolitan, KR;
Creagene, Inc., Gyeonggi-do, KR;
Abstract
The present invention relates to a novel recombinant Sabin type 1 poliovirus vector for the immunogenicity of neutralizing antibody against polioviral infection, which comprises: (a) a genomic nucleotide sequence of a parent Sabin type 1 poliovirus; (b) a nucleotide sequence encoding an additional polioviral cleavage site; and (c) a nucleotide sequence of a conformational epitope encoding a VP1 neutralizing epitope of poliovirus type 2 or 3 and linked to the nucleotide sequence of (b).