The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 14, 2006
Filed:
Dec. 22, 2003
Werner Bonrath, Freiburg, DE;
Claus Dittel, Solothurn, CH;
Lisa Giraudi, Huningue, FR;
Thomas Netscher, Bad Krozingen, DE;
Thomas Pabst, Mintraching, DE;
Werner Bonrath, Freiburg, DE;
Claus Dittel, Solothurn, CH;
Lisa Giraudi, Huningue, FR;
Thomas Netscher, Bad Krozingen, DE;
Thomas Pabst, Mintraching, DE;
DSM IP Assets B.V., Te Heerlen, NL;
Abstract
The present invention is concerned with a novel process for the manufacture of α-tocopheryl acetate which comprises reacting 2,3,6-trimethylhydroquinone-1-acetate with a compound selected from the group consisting of phytol (formula IV with R═OH), iso-phytol (formula III with R═OH), and (iso) phytol derivatives represented by the following formulae III and IV with R═C-to C-alkonoyloxy, benzoyloxy, mesyloxy, bezenesul-fonyloxy or tosyloxy, (IV) in the presence of a catalyst of the formula M(RSO), wherein Mis a silver, copper, gallium, hafnium or rare earth metal cation, n is the valence of the cation M, and Ris fluorine, C-perfluoroalkyl or perfluoroaryl, and, if required, cyclizing any 3-phytyl-2,5,6-trimethylhydroquinone-1-acetate or a double bond isomer thereof obtained as an intermediate reaction product, to produce α-tocopheryl acetate. In the catalyst Mis preferably Ag, Cu, Ga, Sc, Lu, Ho, Tm, Ybor Hf.