The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 14, 2006

Filed:

Jul. 27, 2001
Applicants:

Douglas J. Dellinger, Sunnyvale, CA (US);

Michael G. M. Perbost, Bethany, CT (US);

Marvin H. Caruthers, Boulder, CO (US);

Jason R. Betley, Suffolk, GB;

Inventors:

Douglas J. Dellinger, Sunnyvale, CA (US);

Michael G. M. Perbost, Bethany, CT (US);

Marvin H. Caruthers, Boulder, CO (US);

Jason R. Betley, Suffolk, GB;

Assignees:

Agilent Technologies, Inc., Palo Alto, CA (US);

University of Colorado, Boulder, CO (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H 21/00 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01); A01N 43/04 (2006.01); A61K 31/70 (2006.01);
U.S. Cl.
CPC ...
Abstract

A method of synthesizing a polynucleotide which can, for example, be used during fabrication of an array. A second nucleoside is coupled to a first nucleoside through a phosphite linkage, with the second nucleoside having a hydroxyl protecting group that is a non-carbonate protecting group. The product of the foregoing step is exposed to a composition which both oxidizes the formed phosphite to a phosphate and deprotects the protected hydroxyl of the coupled nucleoside. The method has particular application to fabricating an addressable array of polynucleotides on a substrate which carries substrate bound moieties each with a hydroxyl group.


Find Patent Forward Citations

Dellinger, Douglas. (2006). Synthesis of polynucleotides using combined oxidation/deprotection chemistry (U.S. Patent No. 7135565). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7135565

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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