The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 14, 2006
Filed:
Feb. 04, 2000
Mark Aaron Behlke, Iowa City, IA (US);
Eric Jeffrey Devor, Iowa City, IA (US);
Shale Anthony James, Iowa City, IA (US);
Joseph Alan Walder, Chicago, IL (US);
Mark Aaron Behlke, Iowa City, IA (US);
Eric Jeffrey Devor, Iowa City, IA (US);
Shale Anthony James, Iowa City, IA (US);
Joseph Alan Walder, Chicago, IL (US);
Integrated DNA Technologies, Inc., Skokie, IL (US);
Abstract
The present invention provides novel nucleic acid labeling techniques that generate nucleic acid probes with specific activities at least ten fold higher than the levels obtained using standard labeling methods. Specifically, the methods of the invention provides methods of producing nucleic acid probes that each comprises multiple labeled nucleotides. The methods can be used to generate RNA, DNA or hybrid probes. The invention also provides reaction mixtures and kits for the practice of the methods of the invention and compositions comprising the probes generated according to the methods of the invention.