The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 07, 2006
Filed:
Jun. 02, 2004
Applicants:
Jingwu Duan, Yardley, PA (US);
Chu-biao Xue, Hockessin, DE (US);
James Sheppeck, Newtown, PA (US);
Bin Jiang, Norristown, PA (US);
Lihua Chen, Boothwyn, PA (US);
Inventors:
Jingwu Duan, Yardley, PA (US);
Chu-Biao Xue, Hockessin, DE (US);
James Sheppeck, Newtown, PA (US);
Bin Jiang, Norristown, PA (US);
Lihua Chen, Boothwyn, PA (US);
Assignee:
Bristol-Myers Squibb Company, Princeton, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/147 (2006.01); C07D 453/02 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention provides compounds of Formula (I): or a stereoisomer or pharmaceutically acceptable salt form thereof, wherein the variables L, Z, R, R, R, and Rare defined are as defined herein, which are useful as inhibitors of matrix metalloproteinases (MMP), TNF-α converting enzyme (TACE), aggrecanase, or a combination thereof.