The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 07, 2006

Filed:

Jun. 15, 2004
Applicants:

Nader Fotouhi, Basking Ridge, NJ (US);

Emily Aijun Liu, Basking Ridge, NJ (US);

Binh Thanh VU, North Caldwell, NJ (US);

Inventors:

Nader Fotouhi, Basking Ridge, NJ (US);

Emily Aijun Liu, Basking Ridge, NJ (US);

Binh Thanh Vu, North Caldwell, NJ (US);

Assignee:

Hoffmann-La Roche Inc., Nutley, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/5375 (2006.01); A61K 31/454 (2006.01); A61K 31/496 (2006.01); C07D 401/14 (2006.01); C07D 403/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides compounds according to formula I and pharmaceutically acceptable salts and esters thereof, having the designations provided herein and which inhibit the interaction of MDM2 protein with a p53-like peptide and have antiproliferative activity


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