The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 07, 2006

Filed:

Dec. 13, 2002
Applicants:

Peter Kratzsch, Antdorf, DE;

Rainer Schmuck, Benediktbeuern, DE;

Daniela Beck, Iffeldorf, DE;

Zhixin Shao, Penzberg, DE;

Detlef Thym, Mannheim, DE;

Wolfgang-reinhold Knappe, Ludwigshafen, DE;

Inventors:

Peter Kratzsch, Antdorf, DE;

Rainer Schmuck, Benediktbeuern, DE;

Daniela Beck, Iffeldorf, DE;

Zhixin Shao, Penzberg, DE;

Detlef Thym, Mannheim, DE;

Wolfgang-Reinhold Knappe, Ludwigshafen, DE;

Assignee:

Roche Diagnostics GmbH, Mannheim, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to improved variants of soluble pyrroloquinoline quinone (PQQ)-dependent glucose dehydrogenases (s-GDH), to genes encoding mutated s-GDH, to mutant proteins of s-GDH with improved substrate specificity for glucose, and to different applications of these s-GDH variants, particularly for determining concentrations of sugar, especially of glucose in a sample.


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