The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 31, 2006
Filed:
Aug. 11, 2003
James B. Jaquith, Pincourt, CA;
Alexander Graham Fallis, Ottawa, CA;
John W. Gillard, Baie D'Urfe, CA;
Alain Laurent, Montreal, CA;
James B. Jaquith, Pincourt, CA;
Alexander Graham Fallis, Ottawa, CA;
John W. Gillard, Baie D'Urfe, CA;
Alain Laurent, Montreal, CA;
Aegera Therapeutics Inc., Verdun, CA;
Abstract
This invention features ring-substituted pyrrolo-β-carboline derivatives and ring-substitution and structural derivatives of 3-(1H-indol-3-yl)-1H-pyrrole-2,5-dione of formulas I–III, which are useful as neuroprotective and anti-proliferative compounds. Also disclosed are methods for the preparation of these compounds, selected biological profiles and uses of these compounds in the treatment of various neurodegenerative and inflammatory diseases of the human nervous system and in the treatment of various other proliferative disorders characterized by loss of growth or cellular differentiation control including, but not limited to, cancer and inflammation.