The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 31, 2006
Filed:
Dec. 18, 2001
Ichiro Shima, Osaka, JP;
Takehiko Ohkawa, Osaka, JP;
Kentaro Sato, Osaka, JP;
Naoki Ishibashi, Osaka, JP;
Kenichiro Imamura, Osaka, JP;
Ichiro Shima, Osaka, JP;
Takehiko Ohkawa, Osaka, JP;
Kentaro Sato, Osaka, JP;
Naoki Ishibashi, Osaka, JP;
Kenichiro Imamura, Osaka, JP;
Astellas Pharma Inc., Tokyo, JP;
Abstract
The present invention relates to a compound of the formula (I) wherein R1 is benzofuranyl substituted by halogen, or styryl substituted by halogen; R2 is substituted hydroxy, substituted mercapto or substituted sulfonyl; and X is or pharmaceutically acceptable salts thereof. The compound (1) of the present invention and pharmaceutically acceptable salts thereof possess a strong inhibitory activity on the production of nitric oxide (NO), and are useful for prevention and/or treatment of NO-mediated diseases in human being and animals