The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 31, 2006

Filed:

Jan. 04, 2006
Applicants:

Natalia Aurrecoechea, Oakland, CA (US);

Andrew B. Kelson, San Carlos, CA (US);

Robert W. Macsata, Pleasanton, CA (US);

Louise Robinson, San Carlos, CA (US);

Anthony J. Sanchez, Oakland, CA (US);

Nicholas M. Santiago, San Francisco, CA (US);

Steven R. Schow, Redwood City, CA (US);

Reyna J. Simon, Los Gatos, CA (US);

Inventors:

Natalia Aurrecoechea, Oakland, CA (US);

Andrew B. Kelson, San Carlos, CA (US);

Robert W. Macsata, Pleasanton, CA (US);

Louise Robinson, San Carlos, CA (US);

Anthony J. Sanchez, Oakland, CA (US);

Nicholas M. Santiago, San Francisco, CA (US);

Steven R. Schow, Redwood City, CA (US);

Reyna J. Simon, Los Gatos, CA (US);

Assignee:

Telik, Inc., Palo Alto, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/05 (2006.01); A61K 38/06 (2006.01); C07K 5/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

Tripeptide and tetrapeptide thioethers, pharmaceutical compositions containing them, their pharmaceutical use, and their preparation. The compounds are useful in potentiating the cytotoxic effects of chemotherapeutic agents in tumor cells, selectively exerting toxicity in tumor cells, elevating the production of GM progenitors in bone marrow, stimulating the differentiation of bone marrow, mitigating the myelosuppressive effects of chemotherapeutic agents, and modulating hematopoiesis in bone marrow.


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