The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 31, 2006
Filed:
Jul. 20, 2004
Johan Lowinger, Dexter, MI (US);
Bruno Lowinger, Saline, MI (US);
Frank Delustro, North Charleston, SC (US);
David Cox, Woodbury, MN (US);
David A. Browdie, Scranton, PA (US);
Johan Lowinger, Dexter, MI (US);
Bruno Lowinger, Saline, MI (US);
Frank DeLustro, North Charleston, SC (US);
David Cox, Woodbury, MN (US);
David A. Browdie, Scranton, PA (US);
Covalent Medical, Inc., Ann Arbor, MI (US);
Abstract
A tissue adhesive sealant includes a cross-linkable protein in a solution that when combined with a cross-linking agent solution including an aldehyde and amino acid containing species reactive with the aldehyde cross-links to form a seal. The sealant is well suited for bonding tissue alone or in combination with a patch. The ratio between the aldehyde and the amino acid containing species is between 20:1 and 1:1 on an aldehyde moiety:amino acid or peptide subunit molar basis. Particularly strong seals are formed when the protein and cross-linking agent are present in a molar ratio of between 15:1 and 1:1.