The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 31, 2006
Filed:
Aug. 30, 2000
Joseph Schlessinger, New York, NY (US);
Stevan R. Hubbard, Riverside, NY (US);
Moosa Mohammadi, Scarsdale, NY (US);
Alexander Plotnikov, Emeryville, CA (US);
Zhongtao Zhang, Haworth, NJ (US);
Xiang-peng Kong, New York, NY (US);
Joseph Schlessinger, New York, NY (US);
Stevan R. Hubbard, Riverside, NY (US);
Moosa Mohammadi, Scarsdale, NY (US);
Alexander Plotnikov, Emeryville, CA (US);
Zhongtao Zhang, Haworth, NJ (US);
Xiang-Peng Kong, New York, NY (US);
New York University, New York, NY (US);
Abstract
The determination and use of three dimensional structures of receptor protein tyrosine kinases and/or their ligands are described. One particular group of such structures includes three dimensional structures of the extracellular domain of RPTKs. The three dimensional structures of RPTKs can faciliate the design and identification of modulators of RPTK function. Other such structures can include of RPTK ligands, such as stem cell factor or a fragment thereof. Modulators of RPTK function can be used to treat diseases that are mediated by inappropriate RPTK activity.