The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 24, 2006
Filed:
May. 14, 2003
Kensuke Kobayashi, Tsukuba, JP;
Hirobumi Takahashi, Tsukuba, JP;
Hiroshi Kawamoto, Tsukuba, JP;
Tetsuya Kato, Tsukuba, JP;
Satoru Itoh, Tsukuba, JP;
Takashi Yoshizumi, Tsukuba, JP;
Osamu Okamoto, Tsukuba, JP;
Kensuke Kobayashi, Tsukuba, JP;
Hirobumi Takahashi, Tsukuba, JP;
Hiroshi Kawamoto, Tsukuba, JP;
Tetsuya Kato, Tsukuba, JP;
Satoru Itoh, Tsukuba, JP;
Takashi Yoshizumi, Tsukuba, JP;
Osamu Okamoto, Tsukuba, JP;
Banyu Pharmaceutical Co., Ltd., Tokyo, JP;
Abstract
This invention provides compounds which are represented by a general formula [I] [in which X stands for hydrogen or halogen; B stands for halogen, cyano or optionally fluorine-substituted lower alkyl; D stands for a 3–10 membered aliphatic nitrogen-containing heterocyclic group; R, Rand Rmay be same or different, and each stands for hydrogen, lower alkyl optionally having substituent group(s) and the like; and a is 0 or 1]. These compounds exhibit high affinity to nociceptin receptors and whereby inhibit actions of nociceptin, and are useful as an analgesic, antiobestic, agent for ameliorating brain function, treating agents for Alzheimer's disease and dementia, and therapeutic agents for schizophrenia, neurodegenerative diseases, depression, diabetes insipidus, polyuria, hypotension and the like.