The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 24, 2006
Filed:
Jan. 14, 2003
David A. Cheresh, Encinitas, CA (US);
John Hood, Solana Beach, CA (US);
Martin A. Schwartz, Poway, CA (US);
William B. Kiosses, San Diego, CA (US);
David A. Cheresh, Encinitas, CA (US);
John Hood, Solana Beach, CA (US);
Martin A. Schwartz, Poway, CA (US);
William B. Kiosses, San Diego, CA (US);
The Scripps Research Institute, La Jolla, CA (US);
Abstract
Angiogenesis inhibitors and methods of use thereof are disclosed. The inhibitors are substantially pure oligopeptides consisting essentially of 7–20 amino acid residues and comprising a proline-rich sequence of five amino acid residues PPXPP, SEQ ID NO: 1, wherein X is an amino acid residue selected from the group consisting of alanine, glycine, serine, threonine, valine, leucine and methionine. In a preferred embodiment, the proline-rich polypeptide is covalently bound to a transport molecule such as a Tat-derived transport polypeptide.