The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 24, 2006

Filed:

Jul. 26, 2002
Applicants:

Michael J. Agostino, Andover, MA (US);

Lisa A. Racie, Acton, MA (US);

Inventors:

Michael J. Agostino, Andover, MA (US);

Lisa A. Racie, Acton, MA (US);

Assignee:

Wyeth, Madison, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/48 (2006.01); C12Q 1/37 (2006.01);
U.S. Cl.
CPC ...
Abstract

Novel aggrecanase proteins and the nucleotide sequences encoding them as well as processes for producing them are disclosed. Methods for developing inhibitors of the aggrecanase enzymes and antibodies to the enzymes for treatment of conditions characterized by the degradation of aggrecan are also disclosed.


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