The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 24, 2006

Filed:

Dec. 19, 2002
Applicants:

David P. Yavorsky, Bolton, MA (US);

Jonathan Royce, Merrimack, NH (US);

Matthew Alexander Tomasko, Arlington, MA (US);

Ven Anantha Raman, Salem, NH (US);

Inventors:

David P. Yavorsky, Bolton, MA (US);

Jonathan Royce, Merrimack, NH (US);

Matthew Alexander Tomasko, Arlington, MA (US);

Ven Anantha Raman, Salem, NH (US);

Assignee:

Millipore Corporation, Billerica, MA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
B01D 46/10 (2006.01);
U.S. Cl.
CPC ...
Abstract

A deep gradient-density filter device capable of effectively filtering a fluid containing a distribution of particles in the range of approximately 25 microns to approximately 0.2 micron at a fluid velocity of at least approximately 100 cm/hr and an initial hydraulic permeability of greater than approximately 10 cm/hr/psi. The deep gradient-density filter device includes several layers of filtration material, each having specific predetermined particle retention properties. In one product embodiment, the deep gradient-density filter device uses 'loose' fibrillated cellulose fiber material as a primary filter element. In a method aspect, the deep gradient-density filter device is used for either the secondary clarification of industrial-scale volumes of cultured or fermented protein-containing biopharmaceutical fluids or the primary clarification of pilot-scale volumes.


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