The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 17, 2006

Filed:

Nov. 12, 2002
Applicants:

Gregory A. Reichard, Ann Arbor, MI (US);

Sunil Paliwal, Scotch Plains, NJ (US);

Neng-yang Shih, North Caldwell, NJ (US);

Dong Xiao, Warren, NJ (US);

Hon-chung Tsui, East Brunswick, NJ (US);

Sapna Majmundar Shah, Jamesburg, NJ (US);

Cheng Wang, Summit, NJ (US);

Michelle Laci Wrobleski, Whitehouse Station, NJ (US);

Inventors:

Gregory A. Reichard, Ann Arbor, MI (US);

Sunil Paliwal, Scotch Plains, NJ (US);

Neng-Yang Shih, North Caldwell, NJ (US);

Dong Xiao, Warren, NJ (US);

Hon-Chung Tsui, East Brunswick, NJ (US);

Sapna Majmundar Shah, Jamesburg, NJ (US);

Cheng Wang, Summit, NJ (US);

Michelle Laci Wrobleski, Whitehouse Station, NJ (US);

Assignee:

Scherig Corporation, Kenilworth, NJ (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 207/00 (2006.01); C07D 209/96 (2006.01); C07D 225/00 (2006.01); C07D 215/00 (2006.01); A01N 57/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

A NKantagonist having the formula (I),wherein Arand Arare optionally substituted phenyl or heteroaryl, Xis an ether, thio or imino linkage, Rand Rare not both H or alkyl, and the remaining variables are as defined in the in the specification, useful for treating a number of disorders, including emesis, depression, anxiety and cough. Pharmaceuticals compositions. Methods of treatment and combinations with other agents are also disclosed.


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