The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 17, 2006

Filed:

Aug. 01, 2002
Applicants:

Hubert B. Josien, Hoboken, NJ (US);

John W. Clader, Cranford, NJ (US);

Theodros Asberom, West Orange, NJ (US);

Dmitri A. Pissarnitski, Scotch Plains, NJ (US);

Inventors:

Hubert B. Josien, Hoboken, NJ (US);

John W. Clader, Cranford, NJ (US);

Theodros Asberom, West Orange, NJ (US);

Dmitri A. Pissarnitski, Scotch Plains, NJ (US);

Assignee:

Schering Corporation, Kenilworth, NJ (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 211/56 (2006.01); C07D 409/00 (2006.01); C07D 279/00 (2006.01); A01N 43/40 (2006.01); A61K 31/54 (2006.01);
U.S. Cl.
CPC ...
Abstract

Novel aryl and heteroaryl sulfonamides are disclosed. The sulfonamides, which are gamma secretase inhibitors, are represented by the formula:wherein Arand Arindependently represent aryl or heteroaryl and Y represents a bond or a —(C(R))group. Also disclosed is a method of inhibiting gamma secretase, and a method of treating Alzheimer's disease using the compounds of formula I.


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