The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 17, 2006
Filed:
Aug. 27, 2004
John Charles Kath, Waterford, CT (US);
Daniel Tyler Richter, Groton, CT (US);
Michael Joseph Luzzio, Noank, CT (US);
John Charles Kath, Waterford, CT (US);
Daniel Tyler Richter, Groton, CT (US);
Michael Joseph Luzzio, Noank, CT (US);
Pfizer Inc, New York, NY (US);
Abstract
The present invention relates to a method of making a compound of the formula wherein X, Xand R—Rare as defined herein. The method includes reacting a compound of the formula with an amine of formula 3 (HNRR) in the presence of a Lewis Acid and a non-nucleophilic base. The 2,4-diamino pyrimidine moiety is a common component in a variety of biologically active drug-like molecules and pyrimidine derivatives have been found to be useful in the treatment of abnormal cell growth, such as cancer, in mammals.