The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 17, 2006
Filed:
Jul. 09, 2004
Applicants:
Rudi Beyaert, Zingem, BE;
Sophie Janssens, Ghent, BE;
Inventors:
Rudi Beyaert, Zingem, BE;
Sophie Janssens, Ghent, BE;
Assignees:
Vlaams Interuniversitair Instituut voor Biotechnologie VZW, Zwijnaarde, BE;
Universiteit Gent, Ghent, BE;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/705 (2006.01); C07K 16/28 (2006.01); C07K 1/00 (2006.01); C07H 21/04 (2006.01); C12P 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention relates to the field of infection and inflammation and, more specifically, to the field of pathogen-induced nuclear factor kappa B activation. More specifically, a novel splice variant of MyD88, (MyD88), which has been identified encoding a protein that inhibits LPS-induced NF-κB activation. MyD88is a target to inhibit the phenomenon of endotoxin-tolerance that occurs in sepsis.