The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 17, 2006
Filed:
Apr. 10, 2002
Frances Yen-potin, Vandoeuvre-les-Nancy, FR;
Blake Denison, Dublin, CA (US);
Aymeric Duclert, Saint-Maur, FR;
Lydie Bougueleret, Petit-Lancy, CH;
Catherine Clusel, Vincennes, FR;
Jean-baptiste Dumas Milne Edwards, Paris, FR;
Bernard Bihain, Cancale, FR;
Barbara Bour, San Diego, CA (US);
Dana Ebbets-reed, Encinitas, CA (US);
Luisa Salter-cid, San Diego, CA (US);
Frances Yen-Potin, Vandoeuvre-les-Nancy, FR;
Blake Denison, Dublin, CA (US);
Aymeric Duclert, Saint-Maur, FR;
Lydie Bougueleret, Petit-Lancy, CH;
Catherine Clusel, Vincennes, FR;
Jean-Baptiste Dumas Milne Edwards, Paris, FR;
Bernard Bihain, Cancale, FR;
Barbara Bour, San Diego, CA (US);
Dana Ebbets-Reed, Encinitas, CA (US);
Luisa Salter-Cid, San Diego, CA (US);
Serono Genetics Institute S.A., Evry, FR;
Abstract
The invention provides the genomic sequence of GSSP-2, GSSP-2 cDNAs and GSSP-2 polypeptides. Further the invention provides polynucleotides including biallelic markers derived from the GSSP-2 gene and from genomic regions flanking the gene. This invention also provides polynucleotides and methods suitable for genotyping a nucleic acid molecule containing sample for one or more biallelic markers of the invention. Further, the invention provides methods to detect a statistical correlation between a biallelic marker allele and a phenotype and/or between a biallelic marker haplotype and a phenotype. The invention also concerns methods and compositions for killing neoplastic cells or inhibiting neoplastic cell growth. In particular, the present invention concerns cell proliferation arresting/inhibiting and apoptosis/necrosis inducing compositions and methods for the treatment of tumors. The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides.