The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 17, 2006
Filed:
Apr. 16, 2003
Helmut Robert Macke, Loerrach, DE;
Jean-claude Reubi, Wabern, CH;
Jörg Simon Schmitt, Thal, CH;
Mihaela Ginj, Basel, CH;
Helmut Robert Macke, Loerrach, DE;
Jean-Claude Reubi, Wabern, CH;
Jörg Simon Schmitt, Thal, CH;
Mihaela Ginj, Basel, CH;
BioSynthema Inc., Saint Louis, MO (US);
Abstract
The invention relates to a peptide compound having an improved binding affinity to somatostatin receptors, comprising a somatostatin analogue as the peptide and a chelating group covalently linked to the N-terminal free amino group of said peptide, wherein said somatostatin analogue carries an 1-naphthylalanine or a 3-benzothienylalanine residue in its 3-position. The invention further relates to said peptide compound labeled with a detectable element or with a therapeutic radionuclide, as well as to a diagnostic method and to a method for the therapeutic treatment of tumors, by using the labeled compounds.