The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 17, 2006
Filed:
Aug. 08, 2003
Adnan M. M. Mjalli, Jamestown, NC (US);
Robert C. Andrews, Jamestown, NC (US);
Xiao-chuan Guo, High Point, NC (US);
Daniel Peter Christen, High Point, NC (US);
Devi Reddy Gohimmukkula, Jamestown, NC (US);
Guoxiang Huang, Greensboro, NC (US);
Robert Rothlein, Summerfield, NC (US);
Sameer Tyagi, High Point, NC (US);
Tripura Yaramasu, Greensboro, NC (US);
Christopher Behme, Jamestown, NC (US);
Adnan M. M. Mjalli, Jamestown, NC (US);
Robert C. Andrews, Jamestown, NC (US);
Xiao-Chuan Guo, High Point, NC (US);
Daniel Peter Christen, High Point, NC (US);
Devi Reddy Gohimmukkula, Jamestown, NC (US);
Guoxiang Huang, Greensboro, NC (US);
Robert Rothlein, Summerfield, NC (US);
Sameer Tyagi, High Point, NC (US);
Tripura Yaramasu, Greensboro, NC (US);
Christopher Behme, Jamestown, NC (US);
TransTech Pharma, Inc., High Point, NC (US);
Abstract
This invention provides certain compounds, methods of their preparation, pharmaceutical compositions comprising the compounds, and their use in treating human or animal disorders. The compounds of the invention are useful as antagonists, or more preferably, partial antagonist of factor IX and thus, may be used to inhibit the intrinsic pathway of blood coagulation. The compounds are useful in a variety of applications including the management, treatment and/or control of diseases caused in part by the intrinsic clotting pathway utilizing factor IX. Such diseases or disease states include stroke, myocardial infarction, aneurysm surgery, and deep vein thrombosis associated with surgical procedures, long periods of confinement, and acquired or inherited pro-coagulant states.