The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 17, 2006
Filed:
Apr. 20, 2001
Philip A. Gale, Austin, TX (US);
Jonathan L. Sessler, Austin, TX (US);
Vladimír A. Král, Praha, CZ;
Andrei Andrievsky, Rochester, NY (US);
Vincent Lynch, Austin, TX (US);
Petra I. Sansom, Edgewater, NJ (US);
William E. Allen, Austin, TX (US);
Christopher T. Brown, Austin, TX (US);
Andreas Gebauer, Austin, TX (US);
Philip A. Gale, Austin, TX (US);
Jonathan L. Sessler, Austin, TX (US);
Vladimír A. Král, Praha, CZ;
Andrei Andrievsky, Rochester, NY (US);
Vincent Lynch, Austin, TX (US);
Petra I. Sansom, Edgewater, NJ (US);
William E. Allen, Austin, TX (US);
Christopher T. Brown, Austin, TX (US);
Andreas Gebauer, Austin, TX (US);
Board of Regents, University of Texas System, Austin, TX (US);
Abstract
The present invention provides calixpyrrole, calixpyridinopyrrole, and calixpyridine macrocycles, having 4, 5, 6, 7, or 8 heterocyclic rings, as well as syntheses, derivatives, conjugates, multimers, and solid supports thereof. Such macrocycles have proved to be effective and selective ion- and neutral molecule-binding agents forming supramolecular ensembles, and ion- and neutral molecule-separation agents. The macrocycles are fully meso-non-hydrogen-substituted porphyrinogens, a few molecules of which were previously known but not recognized as possessing anion- or molecule-binding properties. The binding mode is noncovalent, primarily that of hydrogen-bonding, thereby providing a new mode for liquid chromatography, that of Hydrogen Bonding Liquid Chromatography. Further useful applications of the macrocycles provided herein include environmental remediation by removal of undesired ions or neutral molecules, and removal of phosphate for kidney dialysis.