The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 17, 2006

Filed:

Feb. 10, 2004
Applicants:

Peter W. Glunz, Yardley, PA (US);

Gregory S. Bisacchi, Ringoes, NJ (US);

George C. Morton, Collegeville, PA (US);

Alexandra A. Holubec, Yardley, PA (US);

E. Scott Priestley, Yardley, PA (US);

Xiaojun Zhang, Hockessin, DE (US);

Uwe D. Treuner, Nittendorf, DE;

Inventors:

Peter W. Glunz, Yardley, PA (US);

Gregory S. Bisacchi, Ringoes, NJ (US);

George C. Morton, Collegeville, PA (US);

Alexandra A. Holubec, Yardley, PA (US);

E. Scott Priestley, Yardley, PA (US);

Xiaojun Zhang, Hockessin, DE (US);

Uwe D. Treuner, Nittendorf, DE;

Assignee:

Bristol-Myers Squibb Company, Princeton, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/472 (2006.01); C07D 217/22 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds having the formula (I), or a stereoisomer or pharmaceutically-acceptable salt, or hydrate thereof, are useful as factor VIIa inhibitors, wherein X is —NRS(O)R; W is hydrogen or —(CRR)W; Wis hydrogen or a bond with R; Z is a-membered heteroaryl group, a five to six membered heterocyclo or cycloalkyl group, atomembered bicyclic aryl or heteroaryl, or a six membered aryl or heteroaryl, and R, R, R, R, R, and Rare as defined in the specification.


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