The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 17, 2006

Filed:

Nov. 17, 2000
Applicants:

Victor I. Lyamichev, Madison, WI (US);

Michael W. Kaiser, Madison, WI (US);

Natasha Lyamicheva, Madison, WI (US);

Inventors:

Victor I. Lyamichev, Madison, WI (US);

Michael W. Kaiser, Madison, WI (US);

Natasha Lyamicheva, Madison, WI (US);

Assignee:

Third Wave Technologies, Inc., Madison, WI (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/22 (2006.01); C12N 9/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides novel cleavage agents and polymerases for the cleavage and modification of nucleic acid. The cleavage agents and polymerases find use, for example, for the detection and characterization of nucleic acid sequences and variations in nucleic acid sequences. In some embodiments, the 5' nuclease activity of a variety of enzymes is used to cleave a target-dependent cleavage structure, thereby indicating the presence of specific nucleic acid sequences or specific variations thereof.


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