The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 17, 2006

Filed:

Feb. 21, 2003
Applicants:

William C. Olson, Ossining, NY (US);

Paul J. Maddon, Scarsdale, NY (US);

Naoya Tsurushita, Palo Alto, CA (US);

Paul R. Hinton, Sunnyvale, CA (US);

Maximillano Vasquez, Palo Alto, CA (US);

Inventors:

William C. Olson, Ossining, NY (US);

Paul J. Maddon, Scarsdale, NY (US);

Naoya Tsurushita, Palo Alto, CA (US);

Paul R. Hinton, Sunnyvale, CA (US);

Maximillano Vasquez, Palo Alto, CA (US);

Assignees:

Progenics Pharmaceuticals, Inc., Tarrytown, NY (US);

PDL Biopharma, Inc., Fremont, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C12K 16/28 (2006.01); C12N 15/13 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention is directed an anti-CCR5 antibody which comprises (i) two light chains, each light chain comprising the expression product of a plasmid designated pVK:HuPRO140-VK (ATCC Deposit Designation PTA-4097), and (ii) two heavy chains, each heavy chain comprising an expression product of either a plasmid designated pVg4:HuPRO140 HG2-VH (ATCC Deposit Designation PTA-4098) or a plasmid designated pVg4:HuPRO140 (mutB+D+I)-VH (ATCC Deposit Designation PTA-4099) or a fragment thereof which binds to CCR5 on the surface of a human cell.


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