The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 10, 2006
Filed:
Jul. 14, 2003
J. David Lambeth, Atlanta, GA (US);
Guangjie Cheng, Atlanta, GA (US);
James Mccoy, Atlanta, GA (US);
J. David Lambeth, Atlanta, GA (US);
Guangjie Cheng, Atlanta, GA (US);
James McCoy, Atlanta, GA (US);
Emory University, Atlanta, GA (US);
Abstract
The present invention provides a transgenic non-human animal, in particular a transgenic mouse encoding the NOX and Duox family of proteins, which generate reactive oxygen intermediates (ROI). The present invention additionally comprises cells and cell lines containing transgenes encoding for members of the NOX and Duox family of proteins. The present invention further comprises methods and compositions for evaluating regulators of abnormal cell growth and in the development of compounds that effect ROI expression.