The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 10, 2006
Filed:
Jun. 03, 2003
Venkata B. Nanduri, East Brunswick, NJ (US);
Ramesh N. Patel, Bridgewater, NJ (US);
Steven L. Goldberg, Basking Ridge, NJ (US);
Robert M. Johnston, Whitehouse Station, NJ (US);
Venkata B. Nanduri, East Brunswick, NJ (US);
Ramesh N. Patel, Bridgewater, NJ (US);
Steven L. Goldberg, Basking Ridge, NJ (US);
Robert M. Johnston, Whitehouse Station, NJ (US);
Bristol-Myers Squibb Company, Princeton, NJ (US);
Abstract
This invention relates to isolated or recombinant N-carbobenzyloxy-deprotecting enzyme polypeptides, and variants and fragments thereof, that catalyze the removal of carbobenzyloxy from carbobenzyloxy-protected amino acids and alcohols. Also related are isolated nucleic acids encoding N-carbobenzyloxy-deprotecting enzyme polypeptides, and variants, and fragments thereof, as well as vectors and host cells comprising these nucleic acids. The invention also relates to methods of obtaining isolated nucleic acids, polypeptides, and antibodies, and methods of using the polypeptides in various reactions for industrial or pharmaceutical applications.