The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 10, 2006
Filed:
May. 16, 2003
Gerald B. Pier, Brookline, MA (US);
Michael J. Preston, Alan, ME (US);
Lisa Cavacini, Natick, MA (US);
Marshall Posner, Medfield, MA (US);
Gerald B. Pier, Brookline, MA (US);
Michael J. Preston, Alan, ME (US);
Lisa Cavacini, Natick, MA (US);
Marshall Posner, Medfield, MA (US);
The Brigham and Women's Hospital, Inc., Boston, MA (US);
Beth Israel Deaconess Medical Center, Inc., Boston, MA (US);
Abstract
The present invention relates to peptides, particularly human monoclonal antibodies, that bind specifically tomucoid exopolysaccharide. The invention further provides methods for using these peptides in the diagnosis, prophylaxis and therapy ofinfection and related disorders (e.g., cystic fibrosis). Some antibodies of the invention enhance opsonophagocytic killing of multiple mucoid strains of. Compositions of these peptides, including pharmaceutical compositions, are also provided, as are functionally equivalent variants of such peptides.