The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 10, 2006

Filed:

Dec. 02, 2004
Applicants:

Zhidong Chen, New Milford, CT (US);

Pier Francesco Cirillo, Woodbury, CT (US);

Darren Disalvo, New Milford, CT (US);

Weimin Liu, Sandy Hook, CT (US);

Daniel Richard Marshall, Sandy Hook, CT (US);

Lifen Wu, New Milford, CT (US);

Erick Richard Roush Young, Danbury, CT (US);

Inventors:

Zhidong Chen, New Milford, CT (US);

Pier Francesco Cirillo, Woodbury, CT (US);

Darren DiSalvo, New Milford, CT (US);

Weimin Liu, Sandy Hook, CT (US);

Daniel Richard Marshall, Sandy Hook, CT (US);

Lifen Wu, New Milford, CT (US);

Erick Richard Roush Young, Danbury, CT (US);

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4365 (2006.01); A61K 31/506 (2006.01); A61K 31/5377 (2006.01); C07D 413/14 (2006.01); C07D 409/14 (2006.01);
U.S. Cl.
CPC ...
Abstract

Disclosed are compounds of formula (I): wherein the variables R, R, Rand Z are described herein, which are useful as inhibitors of the kinase activity of the IκB kinase (IKK) complex. The compounds are therefore useful in the treatment of IKK mediated diseases including autoimmune diseases inflammatory diseases and cancer. Also disclosed are pharmaceutical compositions comprising these compounds and processes for preparing these compounds.


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