The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 10, 2006
Filed:
Mar. 15, 2000
Ronald M. Evans, La Jolla, CA (US);
Michael B. Mckeown, San Diego, CA (US);
Anthony E. Oro, San Diego, CA (US);
William A. Segraves, Ambler, PA (US);
Tso-pang Yao, La Jolla, CA (US);
Ronald M. Evans, La Jolla, CA (US);
Michael B. McKeown, San Diego, CA (US);
Anthony E. Oro, San Diego, CA (US);
William A. Segraves, Ambler, PA (US);
Tso-Pang Yao, La Jolla, CA (US);
The Salk Institute for Biological Studies, La Jolla, CA (US);
Abstract
In accordance with the present invention, it has been discovered that various members of the steroid/thyroid superfamily of receptors can interact with the insect-derived ultraspiracle receptor, to form multimeric species. Accordingly, the interaction of at least one member of the steroid/thyroid superfamily of receptors with at least the dimerization domain of the ultraspiracle receptor modulates the ability of said member of the steroid/thyroid superfamily of receptors to transactivate transcription of genes maintained under hormone expression control in the presence of the cognate ligand for said member of the superfamily.