The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 10, 2006
Filed:
Feb. 12, 2002
Shyam S. Mohapatra, Tampa, FL (US);
Mukesh Kumar, Norwood, MA (US);
Shua-ku Huang, Towson, MD (US);
Kam Leong, Ellicott City, MD (US);
Shyam S. Mohapatra, Tampa, FL (US);
Mukesh Kumar, Norwood, MA (US);
Shua-ku Huang, Towson, MD (US);
Kam Leong, Ellicott City, MD (US);
University of South Florida Board of Trustees, Tampa, FL (US);
Johns Hopkins University, Baltimore, MD (US);
Abstract
An effective prophylactic mucosal gene expression vaccine (GXV), made up of a cocktail of at least 4 different plasmid DNAs encoding corresponding RSV antigens, coacervated with chitosan to formulate nanospheres. In a murine model of RSV infection, intranasal administration with GXV results in significant induction of RSV-specific antibodies, nasal IgA antibodies, cytotoxic T lymphocytes, and IFN-γ production in the lung and splenocytes. A single dose of GXV induces a drastic reduction of viral titers.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile