The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 10, 2006

Filed:

Jun. 09, 2000
Applicants:

Erika Hawkins, Madison, WI (US);

John M. Centanni, Madison, WI (US);

Jacqueline Sankbeil, Edgerton, WI (US);

Keith V. Wood, Madison, WI (US);

Inventors:

Erika Hawkins, Madison, WI (US);

John M. Centanni, Madison, WI (US);

Jacqueline Sankbeil, Edgerton, WI (US);

Keith V. Wood, Madison, WI (US);

Assignee:

Promega Corporation, Madison, WI (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/66 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides kits and methods for increasing the sensitivity of a bio-luminescent assay, which employ an organic compound that, for instance, reduces luminescence that is not dependent on the presence of an analyte by at least about 10 fold and reduces luminescence that is dependent on the presence of an analyte by less than about 7 fold, reduces luminescence generated by luminogenic molecules not bound to an enzyme by at least about 10 fold and reduces the luminescence generated by luminogenic molecules bound to an enzyme by less than about 7 fold, or reduces autoluminescence by at least about 10 fold and reduces luminescence that is dependent on the presence of an analyte by less than about 7 fold.


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