The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 10, 2006
Filed:
Sep. 28, 2001
X. Charlene Liao, Palo Alto, CA (US);
Peter Chu, San Francisco, CA (US);
Jorge Pardo, San Francisco, CA (US);
Congfen LI, Davis, CA (US);
Haoran Zhao, Foster City, CA (US);
Jun Wu, Sunnyvale, CA (US);
X. Charlene Liao, Palo Alto, CA (US);
Peter Chu, San Francisco, CA (US);
Jorge Pardo, San Francisco, CA (US);
Congfen Li, Davis, CA (US);
Haoran Zhao, Foster City, CA (US);
Jun Wu, Sunnyvale, CA (US);
Rigel Pharmaceuticals, Inc., South San Francisco, CA (US);
Abstract
The present invention relates to regulation of lymphocyte activation. More particularly, the present invention is directed to nucleic acids encoding PAK2, which is involved in modulation of lymphocyte activation. The invention further relates to methods for identifying and using agents, including small organic molecules, peptides, circular peptides, antibodies, lipids, antisense nucleic acids, and ribozymes, that modulate lymphocyte activation via modulation of PAK2; as well as to the use of expression profiles and compositions in diagnosis and therapy related to lymphocyte activation and suppression.