The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 03, 2006
Filed:
Mar. 14, 2003
Susumu Seino, Aoba-cho, Chuo-ku, Chiba-shi 260-0852, JP;
Takashi Miki, Chiba, JP;
Haruaki Nakaya, Chiba, JP;
Susumu Seino, Aoba-cho, Chuo-ku, Chiba-shi 260-0852, JP;
Takashi Miki, Chiba, JP;
Haruaki Nakaya, Chiba, JP;
JCR Pharmaceuticals Co., Ltd., Ashiya, JP;
Other;
Abstract
Mice homozygous for the lack of inward-rectifying potassium channel Kir6.1 gene are disclosed. The mice causes a high incidence of sudden death associated with arrhythmia (atrioventricular block) caused by spontaneous cardiac ischemia, a condition similar to Prinzmetal angina (variant angina) in human, representing an animal model of Prinzmetal angina. Mice heterozygous for the lack of inward-rectifying potassium channel Kir6.1 gene are also disclosed, which are used as parent mice for reproduction of the homozygous mice.