The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 03, 2006

Filed:

Feb. 06, 2003
Applicant:

Frederick Khachik, Rockville, MD (US);

Inventor:

Frederick Khachik, Rockville, MD (US);

Assignee:

University of Maryland, College Park, College Park, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 35/21 (2006.01); C07C 35/18 (2006.01); C07C 41/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to a method of reacting (3R,3'R,6′R)-lutein with a catalytic amount of an acid to obtain a mixture of anhydroluteins, rich in anhydrolutein III, with substantially no Z-isomers being formed. The mixture is converted to (3R)-β-cryptoxanthin (major product) and (3R,6′R)-α-cryptoxanthin (minor product) by reacting the anhydroluteins with borane-amine complexes (e.g. MeN.BH) or other hydride donors and an acid in a chlorinated solvent, preferably dichloromethane, at ambient temperature to produce (3R)-β-cryptoxanthin and (3R,6′R)-α-cryptoxanthin.


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