The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 03, 2006

Filed:

Apr. 02, 2004
Applicants:

Yi Chen, Nutley, NJ (US);

Apostolos Dermatakis, Parlin, NJ (US);

Jin-jun Liu, Warren, NJ (US);

Kin-chun Luk, North Caldwell, NJ (US);

Christophe Michoud, New York, NY (US);

Pamela Loreen Rossman, Nutley, NJ (US);

Inventors:

Yi Chen, Nutley, NJ (US);

Apostolos Dermatakis, Parlin, NJ (US);

Jin-Jun Liu, Warren, NJ (US);

Kin-Chun Luk, North Caldwell, NJ (US);

Christophe Michoud, New York, NY (US);

Pamela Loreen Rossman, Nutley, NJ (US);

Assignee:

Hoffmann-la Roche Inc., Nutley, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); C07D 239/47 (2006.01); C07D 407/12 (2006.01); A61K 31/519 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Disclosed are novel pyrimido compounds that are selective inhibitors of both KDR and FGFR kinases. These compounds and their pharmaceutically acceptable salts are anti-proliferative agents useful in the treatment or control of solid tumors, in particular breast, colon, lung and prostate tumors. Also disclosed are pharmaceutical compositions containing these compounds and methods of treating cancer.


Find Patent Forward Citations

Loading…