The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 03, 2006

Filed:

Jan. 29, 2003
Applicants:

Akira Nakagawa, Fuchu-shi, Tokyo 183-0035, JP;

Senji Takahashi, Tokyo, JP;

Toshitsugu Miyazaki, Kobe, JP;

Yuuko Osanai, Saitama, JP;

Kunio Kosaka, Tokyo, JP;

Koji Nagai, Tokyo, JP;

Nakako Arao, Tokyo, JP;

Kouichi Tanaka, Tokyo, JP;

Inventors:

Akira Nakagawa, Fuchu-shi, Tokyo 183-0035, JP;

Senji Takahashi, Tokyo, JP;

Toshitsugu Miyazaki, Kobe, JP;

Yuuko Osanai, Saitama, JP;

Kunio Kosaka, Tokyo, JP;

Koji Nagai, Tokyo, JP;

Nakako Arao, Tokyo, JP;

Kouichi Tanaka, Tokyo, JP;

Assignees:

Astellas Pharma Inc., Tokyo, JP;

Other;

Nagase & Co., Ltd,, Osaka, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H 15/00 (2006.01); C07H 17/00 (2006.01); A61K 8/00 (2006.01); A61Q 5/08 (2006.01);
U.S. Cl.
CPC ...
Abstract

There are provided a novel microorganismsp. B20 strain which produces (E)-4-(2-isocyanovinyl)phenyl α-rhamnopyranoside having a favorable effect of inhibiting melanogenesis and α-L-rhamnopyranoside produced thereby. This novel microorganism is a gram-negative bacillus isolated from soil and shows motility owing to polar flagellum. The α-L-rhamnopyranoside, which is produced by culturing the microorganism under aerobic conditions at a culture temperature of 10 to 37° C. and at a medium pH of about 5 to 9 usually for about 1 to 7 days, is useful as a highly safe and stable whitening agent.


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